The in vitro cytotoxicity test determines whether a product or compound will have toxic effects on living cells. It is performed following different Standards according to the client's needs, ISO 10993-5, USP or other Pharmacopeias are the most required.

It is a fast, standardized and sensitive way to evaluate raw materials and finished medical products.

There are different methods to perform the in vitro Cytotoxicity test, some are qualitative and others quantitative. They evaluate different parameters and cellular activities and this can lead to obtaining results, also different, for the same PM.

Our experts work with clients to guide them in choosing the most suitable cytotoxicity test method for the type of sample to be tested (liquid, solid, raw material, finished PM, etc.)

MTT cytotoxicity: is a quantitative test that measures the activity of a mitochondrial enzyme

Agar diffusion cytotoxicity: is a qualitative test that evaluates the integrity of the cell membrane

Elution cytotoxicity: is a qualitative test that evaluates cell morphology and replication capacity.

Cytotoxicity in vitro

Biocompatibility tests